Tài liệu miễn phí Sức khỏe phụ nữ
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Bài giảng Siêu âm Doppler phụ khoa
Nội dung của bài giảng trình bày công thức Doppler; các loại hình Doppler; ứng dụng Doppler trong sản khoa. Mời các bạn cùng tham khảo bài giảng để nắm chắc kiến thức.
1/12/2020 6:16:03 PM +00:00
Bài giảng Siêu âm Doppler phụ khoa – BS. Jasmine Thanh Xuân
bài giảng thông tin đến các bạn những kiến thức: đại cương; giải phẫu mạch máu sinh dục nữ; sinh lý huyết động học và dạng phổ doppler bình thường; kỹ thuật siêu âm doppler; ứng dụng trong chẩn đoán. Mời các bạn cùng tham khảo bài giảng để nắm chắc kiến thức.
1/12/2020 6:15:53 PM +00:00
Bài giảng Siêu âm phụ khoa
Nội dung của bài giảng trình bày siêu âm phụ khoa theo chu kỳ kinh nguyệt, phát hiện các khối u tử cung, buồng trứng; chẩn đoán chửa ngoài tử cung; chẩn đoán viêm nhiễm của phần phụ; theo dõi kích thích phóng noãn; chụp buồng tử cung bằng siêu âm; siêu âm tầng sinh môn.
1/12/2020 6:15:41 PM +00:00
Bài giảng Nghiên cứu áp dụng phân loại Gi-Rads trên siêu âm trong chẩn đoán khối u buồng trứng - BS. Trần Nhật Quỳnh
Bài giảng xác định các đặc điểm siêu âm theo phân nhóm và phân loại GI-RADS các khối u thực thể của buồng trứng; khảo sát giá trị dự đoán của các đặc điểm siêu âm và phân loại GI-RADS trong chẩn đoán khối u buồng trứng...
1/12/2020 6:13:55 PM +00:00
Bài giảng Đo chiều dài cổ tử cung & mép dưới bánh nhau đến lỗ trong CTC để có dự hậu tốt - PGS. Susan Campbell Westerway
Bài giảng trình bày tổng quan đo chiều dài cổ tử cung và mép dưới bánh nhau đến lỗ trong CTC để có dự hậu tốt; siêu âm bụng với siêu âm âm đạo; đo chiều dài CTC, siêu âm bụng, mép dưới bánh nhau đến cổ tử cung...
1/12/2020 6:13:44 PM +00:00
Comparative antimicrobial efficacy evaluation of aqueous and alcoholic extracts of Ayurvedic vaginal formulation for treatment of vaginitis
This in-vitro study evaluates the antibacterial &antifungal action of aqueous & alcoholic extracts of new herbal vaginal formulation containing equal amounts of Symplocos racemosa Roxb. and Ficus glomerata Roxb. stem barks against gram positive and gram negative bacteria and candid fungus by using the methods of zone of inhibition and minimum inhibition concentration (MIC) to assess its efficacy in treating vaginitis. During phytochemical analysis, alkaloids, flavonoids, tannins and carbohydrates were found to be present in both extracts. Total phenol content (TPC) determined using the Folin- Ciocalteu reagent was found to be 225.67 and 220.00µg Gallic acid equivalent/mg in the aqueous and alcoholic extract respectively. The results of minimum inhibition concentration study suggest higher antimicrobial activity by the alcoholic extract than the aqueous extract and more pronounced antibacterial action than the anti-fungal action by both extracts. The MIC values were also higher in case of fungal species as compared to all the bacterial species, while among the bacterial species, MIC was found to be higher in case of gram negative bacteria than gram positive bacteria except Staphylococcus aureus. Determination of the diameter of zone of inhibition during disk diffusion study suggested higher antibacterial action than anti-fungal action, and stronger antibacterial effect upon Gram positive bacteria than Gram negative bacteria by all extracts. The alcoholic extract exhibited higher zones of inhibition than aqueous extract for all antimicrobial categories. Similarly, antimicrobial efficacy of alcoholic extract using 8 mg per disk drug dosage was a little lower but comparable to effect of the standard drugs at 10µg/disc level. The overall antimicrobial effect of the research extracts was significant and comparable but a little lower when compared to the standard drugs.
1/12/2020 5:19:22 PM +00:00
Impact of iron rich food supplementation on poor anemic rural pregnant women and adolescent girls
Impact of iron rich food supplementation on poor anemic rural pregnant women and adolescent girls
1/12/2020 4:46:22 PM +00:00
Elderly women in unorganized sector: A study in hisar
An elderly or old age woman comprises the later part of life; the period of life after youth and middle age. The elderly women lived in vulnerable conditions and don’t have any vocational skills in order to earn their livelihood as their whole life is spent doing household work and their physical health didn’t allowed them to work. They faced vulnerability in the psychological, economical, physical and social areas. The elderly women in unorganized sector were living in susceptible conditions and they were given less importance. It was important to understand the problems faced by the elderly in unorganized sector and the conditions under which they are living. By keeping in view the above scenario, the present study was conducted with first objective i.e., to study the current scenario of elderly women working in unorganized sector in Hisar. Second objective was to understand the socio-economic background and relationship of the elderly women with their family members. To study the elderly women workers in unorganized sectors, 100 respondents were selected through the convenient sampling method. It was found that majority of the elderly had average kind of health. One-fourth of the respondents were having fairly good health status. Few of them were unaware about their health status due to the lack of knowledge regarding health. Most of the elderly stays with chief earner of the family whereas one-third of the respondents do not stay with chief earner. As far as support of family is concerned, it was reported that half of the elderly women were not supported by their son whereas one-third of elderly were found to be supported by their family. In order to become familiar with elderly women’s problems it is important to study elderly women in unorganized sector so that possible steps can be taken to improve their present status.
1/12/2020 11:27:18 AM +00:00
Tìm hiểu nhận thức của phụ nữ mang thai ở thành phố Cao Lãnh tỉnh Đồng Tháp về bệnh trầm cảm sau sinh
Bài báo này trình bày kết quả nghiên cứu về nhận thức của phụ nữ mang thai về bệnh trầm cảm sau sinh. Nghiên cứu được thực hiện bằng phương pháp nghiên cứu tài liệu kết hợp với phương pháp khảo sát bằng bảng hỏi với số lượng 100 người phụ nữ đang mang thai được lựa chọn một cách ngẫu nhiên trên địa bàn Thành phố Cao Lãnh, tỉnh Đồng Tháp. Từ những đánh giá, chúng tôi đề ra những giải pháp giúp cho phụ nữ nhìn nhận rõ ràng hơn về bệnh trầm cảm sau sinh cũng như các cách để phụ nữ vượt qua tình trạng đó.
1/12/2020 10:54:43 AM +00:00
Reproductive health knowledge of rural mothers of Hisar district, India
The present study aimed at assessing levels of reproductive health knowledge of rural mothers. Reproductive health covers various aspects such as family planning, STD, AIDS, infant mortality, contraceptives, antenatal care etc. The sample consisted of 300 rural mothers, from Hisar district of Haryana state, having children below 5 years of age. The knowledge was assessed using Reproductive Health Knowledge Checklist developed under All India Coordinated Research Project, ICAR. The checklist categorized the knowledge levels as low, average and high. Information on personal variables of the respondents viz. education level, family income, husband’s occupation, caste, number of children and newspaper subscription was obtained using a self- structured interview schedule. Frequencies, percentages, correlation and chi-square were used to analyze the data. Monthly income of most of the respondent was Rs.5000-Rs.20000. Most of them were educated up to matric or 10+2, belonged to SC/ST community, had four children and subscribed no newspaper. The level of reproductive health knowledge of majority of rural mothers was high and it was found to be positively and significantly correlated with their education level. Chi square test revealed that there was no significant association between reproductive health knowledge of mothers and their personal variables except their education level. So, it can be concluded that educated rural women have better knowledge of reproductive health.
1/12/2020 10:15:37 AM +00:00
Toxoplasma sero-prevalence and related knowledge survey in pregnant women and university staff
Toxoplsmosis is a disease of all regions and communities. The present study was conducted in 2017 to evaluate Toxoplasma prevalence and related knowledge in pregnant women and university staff of Kirkuk city.1000 individuals had submitted a questionnaire form to assess their knowledge on Toxoplasma. Sero-prevalence screen of the disease was done by ELIZA technique in 276 individuals of the pregnant women. The total infection rate of the disease among the pregnant women was 9.8%. Entirely the educated persons had more knowledge background on toxoplasmosis comparing to uneducated, in both university staff and pregnant women. The proportion of university staff who knew what is the disease was 41.4 %. While a proportion of 58.6% did not knew the disease. Among pregnant women a proportion of 35.3% had knew some information on the disease and a rate of 64.7% of them were only heard on the disease. Very high percentages of questioned cohorts have no information on the diseases host types, modes of transmission, infected body organs, populations more at risk for getting the infection and other diseases related knowledge's because the disease is more related to women than men. These results highlight the significance of a regular seminars and conferences on toxoplasmosis among females especially pregnant, as well as the importance of periodically serological screening process during prenatal care.
1/12/2020 10:07:17 AM +00:00
Azole resistance in Candida species isolated from diabetic women with vulvovaginal Candidiasis in a tertiary care centre
This study shows that the isolation of non-albicans Candida have clinical implications due to their reduced susceptibility to various antifungals, thus highlighting the importance of isolation, species identification and antifungal susceptibility testing prior to initiation of therapy for proper selection of antifungal agent. The judicious use of antifungal agents is very important for the prevention of emergence and spread of drug resistant Candida species.
1/12/2020 8:36:50 AM +00:00
A study on menstruation and personal hygiene among adolescent girls
Adolescence is a transition period from childhood to adult life during which pubertal development and sexual maturation take place, thus making physiological development a challenge adolescents have to face. There is a substantial lacuna in the knowledge towards menstruation among adolescent girls; hence, an attempt was made to study on Menstruation and Personal hygiene among Adolescent girls. Ex post facto research design was used for the study. The locale of the study was Midjil of Mahabubnagar district in Telangana State. Sample size of 30 adolescent school going girls of age group 12 to 16 years were purposively selected. Structured questionnaire was used to examine the existing knowledge and hygiene practices regarding menstruation. Frequencies and percentages were used to analyse the collected data. Results revealed that prior information about menarche before its attainment was not available to 53% of the adolescent girls in the present study. About 30% of the respondents use sanitary pads during their periods. Majority (77%) of the adolescent girls did not change their pads or cloths more than two times during menstruation and, hence indicated low hygiene practice during menstruation.
1/12/2020 8:22:49 AM +00:00
Infertility in a crossbred cattle as a sequel to uterine form of tuberculosis
The current report presents a rarest case of uterine tuberculosis in cattle. A seven years old crossbred cattle having completed two normal parities developed infertility, as it was not able to conceive after various attempts of artificial inseminations. The clinical parameters of animal were often reported in normal range over repeated examinations except for slight loss of condition. The cause of infertility was ascertained through a positive intradermal tuberculin test and presence of multiple raised nodules in both uterine horns appreciable upon ultrasonography.
1/12/2020 5:47:14 AM +00:00
The associations of serum AMH, vitamin D, FSH and AFC in different age groups of infertile women
The objective of our study was to identify the associations between the tests that used in ovarian reserve assessment: Anti-Mullerian hormone (AMH), follicle stimulating hormone (FSH) and antral follicle count (AFC) and to distinguish the most reliable markers for ovarian reserve in order to select an adequate strategy for the initial stages of infertility treatment and identify the effect of vitamin D on the ovarian reserve and its correlation with AMH. Anti-mullerian hormone (AMH) is expressed only in the gonads. In female it’s secreted by adult granulosa cells of the ovary. The levels of AMH reflect the number of preantral follicles and thus as a marker of oocyte pool which is a germinal reserve of the ovary for reproduction. Vitamin D is a fat-soluble vitamin that belongs to the family of steroid hormones. It has a biologically plausible role in female reproduction. In this paper AMH, FSH and Vitamin D was determined by enzyme linked immunosorbent assay in: 60 infertile women with PCOS (cases) undergoing IVF and 30 healthy women had one child at least (control). The antral follicle count (AFC) was recorded for each female in case group. The AMH and 25(OH) D levels in cases were lower than that of control, while FSH level in cases was higher than control group. The AMH in cases was significantly decreased with increasing age.
1/12/2020 5:41:44 AM +00:00
Serological study of Toxoplasmosis by line immune assay (LIA) in women with bad obstetric history
One of the tragedies that confront the pregnant woman and physician providing obstetric care is the occurrence of fetal death. It is reported that toxoplasmosis, one among protozoal infections have a high incidence in pregnancy, sometimes causing fetal death. Toxoplasmosis is caused by a coccidian parasite, Toxoplasma gondii which is highly prevalent both in humans and warm-blooded animals. The study was intended to observe the prevalence of Toxoplasmosis in pregnant women presenting with bad obstetric history (BOH). A total of 100 antenatal women with bad obstetric history were included in the study and tested for toxoplasmosis infection. All the samples were screened by Line Immuno Assay (LIA) using recomLineTORCH ScreeningI gG/IgM antibody kits against TORCH agents. Out of the 100 antenatal women in the study group, 4 were seropositive for IgM, 31 cases were positive for IgG and 5 cases were positive for both IgM and IgG of Toxoplasma. Out of 100 patients, Toxoplasma was seen in36.36% in abortion, 53.84% in congenital anomalies, 40% in neonatal death, 33.33% in intrauterine death and 7.6% in congenital anomalies.LIA was found to be a sensitive serological test for diagnosis of Toxoplasmosis in pregnant women with BOH.
1/12/2020 5:30:33 AM +00:00
Diagnosis and treatment procedures involved for young female patients having fibroadenoma
Fibroadenoma‟, is the most common benign tumors among most of the young female patients who are in their adolescent phase. They can be asymptomatic or painful and sometimes develop as tumors which cause distortions of breast. Here we have conducted a descriptive 6 months survey from April to September, 2018 at Dr. Bholanath Chakravarty Integrated Medical Research and Treatment Centre. All the clinical records along with the consent of the patients were taken and recorded for future analysis. It was observed that among selected 113 patients attending the OPD, 11 patients (9.73%) were found as confirmed cases of fibroadenoma via diagnostic techniques ultrasonography and X-Ray Mammogram. Fibroadenomas are more frequent among married woman than unmarried woman. The factors such as early marriage and parity, age of menarche and age of menopause, hormonal therapy such as intake of oral contraceptives have no effect on these lesions. Our study revealed that the incidence percentage of fibroadenoma out of 113 cases were 11 (9.73%). Patients who undergo conservative therapy involves combination of progesterone and danazol as it is the most accepted theory for the treatment.
1/12/2020 5:18:55 AM +00:00
Khảo sát kết quả sử dụng kháng sinh dự phòng trong mổ lấy thai tại Khoa Phụ sản, Bệnh viện Quân y 103
Bài viết khảo sát kết quả sử dụng kháng sinh dự phòng trong mổ lấy thai tại Khoa Phụ sản, Bệnh viện Quân y 103. Đối tượng và phương pháp: nghiên cứu hồi cứu 172 bệnh nhân mổ lấy thai sử dụng kháng sinh dự phòng tại Khoa Phụ sản, Bệnh viện Quân y 103 từ 06 - 2016 đến 06 - 2017. Kết quả: tuổi trung bình nhóm nghiên cứu: 30,07 ± 4,18; con rạ lần 2: 77,9%; mổ lấy thai vì vết mổ đẻ cũ: 57%; thời gian chờ phẫu thuật: 2,94 ± 0,94 giờ; mổ trong 3 giờ đầu: 76,8%; nhóm có bạch cầu > 10 G/l là 59,4%. Thời gian phẫu thuật trung bình 54,7 ± 10,5 phút; thời gian nằm viện trung bình 3,13 ± 0,46 ngày; nằm 3 ngày 87,8%; sử dụng kháng sinh dự phòng thành công 97,6%. Kết luận: khuyến cáo sử dụng kháng sinh dự phòng với chỉ định rộng hơn cho các bệnh nhân mổ lấy thai.
1/11/2020 11:44:48 PM +00:00
Hiệu quả của phương pháp bơm tinh trùng vào tử cung dùng letrozole kích thích buồng trứng trên phụ nữ buồng trứng kích thích đa nang
Bài viết đánh giá hiệu quả và độ an toàn của letrozole đối với kích thích buồng trứng và mang thai ở bệnh nhân có hội chứng buồng trứng đa nang và phân tích tình trạng kháng insulin ở những bệnh nhân này. Đối tượng và phương pháp: nghiên cứu mô tả tiến cứu có so sánh hai nhóm: 40 phụ nữ vô sinh có hội chứng buồng trứng đa nang (nhóm nghiên cứu) và 40 phụ nữ vô sinh không do hội chứng buồng trứng đa nang (nhóm chứng) được điều trị tại Viện Mô phôi Lâm sàng Quân đội.
1/11/2020 11:42:48 PM +00:00
Visual position and juxtaposition: An analytical study of liberty leading the people and moon-woman cuts the circle
This paper explores the idea of romantic and modern painting with the reference of Delacroix’s painting “ Liberty Leading the People” and Jackson Pollock’s painting “Moon Woman Cuts the Circle”. Both painters representing different era, portray different styles, background, color, tempo, and textures in their painting. Delacroix’s painting expresses inner emotions and realistic world. His painting is emotional, it seems to be natural and exotic. He has used arches, sculptures, and gray color dominantly. In contrast to Delacroix, Pollock’s painting is experimental. It has abstraction and two-dimensionality.
11/29/2019 7:38:55 PM +00:00
Mother’s education and antenatal care visits in Nepal
The proper use of antenatal care (ANC) visit is the first step to prevent both mother and child health. This is also one of the key components to achieve the Sustainable Development Goals by 2030. The study is an attempt to assess the relation between mother’s education and utilization of ANC services in Nepal. It is completely based on data of national representative 2016 Nepal Demographic and Health Survey that covered 2,746 currently married women, aged 15-49 years who had at least one child in the last three years preceding the survey. Logistic regression was used to analyze the effect of education on the utilization of ANC services. Results showed that a higher level of maternal education increased the chance of utilizing ANC services than those with little or no education. The importance of maternal education continued even when other socioeconomic factors are taken into account. This indicates that mother’s education contribute to increase the use of proper ANC services.
11/29/2019 7:38:44 PM +00:00
Use of contraceptive methods among young married women in Nepal
Nepal has a fairly high adolescent fertility rate and low use of contraception. Lack of contraceptive use is a major contributor to the high rates of unintended pregnancies amongst youth. There is also lack of specific studies dealing with contraceptive behavior among young married women. This study examines the use and determinants of contraceptive methods over the time period of 15 years (2001-2016) among young women in Nepal. Trend and bi-vatiate analysis of this study is based on the Nepal Demographic and Health Survey (NDHS), 2001, 2006, 2011 and 2016 data. The multivariate analysis is based on NDHS 2016 data of 2059 currently married non-pregnant young women aged 15-24 years. Logistic regression is used to assess the net effect of independent variables on dependent variable. The study shows that the contraceptive prevalence rate of young women is only 34 percent. Number of living children, spousal separation, husband education, women, occupation, wealth status, caste/ethnic affiliation, fertility preference, decision making status, ideal number of children they prefer and media exposure, are statistically associated to the use of contraception among young women in Nepal. There is a need to strengthen income generating activities so as to improve young women's socio-economic status which will translate into female economic and social empowerment hence ability to discuss sexuality related issues. Family planning programmes should be designed so as to address the contraceptive need of young women especially the low parity and Muslim adolescents.
11/29/2019 7:38:32 PM +00:00
Reproductive outcome, hormone levels and liver enzymes in agricultural female workers
The study aimed to explore the effects of exposure to pesticides on the reproductive health and liver function of females participating in agricultural work. Blood samples were obtained from the thirty-five females (out of one hundred females of reproductive age) who were willing to donate blood. Fifty females matched for age and socio economic status were recruited as a control group to compare levels of hormones (estradiol, progesterone and follicle stimulating hormone), liver enzymes alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Results showed that 53% of the females examined in this village were illiterate. Agricultural work represented 42% of the occupations encountered by females in the study. Females who helped in farming operations showed a higher incidence of adverse pregnancy outcome such as abortions and stillbirths compared to those who did not share in agricultural work. There was a significant elevation in estradiol and progesterone levels among female agricultural workers and controls. There was also elevation in serum liver enzymes (AST and ALT) in agricultural workers compared to the controls. However, there was a significant decrease in FSH level in females sharing in agricultural activities compared to the controls. It could be concluded that participation of females in agricultural activities with potential exposure to pesticides endangers their reproductive health and liver functions. Rural areas in Egypt require more attention to increase the percentage of literacy among females and raise their health awareness.
11/29/2019 4:07:27 PM +00:00
Pilot study of classic galactosemia: Neurodevelopmental impact and other complications urge neonatal screening in Egypt
Classic galactosemia is caused by deficiency of galactose-1-phosphate uridylyltransferase (GALT). It causes serious morbidity and mortality if left untreated. Screening for galactosemia is not included in Egyptian neonatal screening program. The study aimed to define clinical presentation and complications of galactosemia at Pediatric Hepatology Clinic, Cairo University, Egypt. Thus, the clinical presentation, course and outcome of 37 children with documented galactosemia was studied. Jaundice was the main presentation (67.6%). Other presentations included; convulsions (29.7%), motor retardation (24.3%), mental retardation (5.4%), microcephaly (5.4%), failure to thrive (16.2%), hepatomegaly (62.2%), splenomegaly (35.1%), vomiting (16.2%), diarrhea (8.1%), liver cell failure (10.8%), renal tubular acidosis (5.4%), cataract (5.4%), autoimmune hepatitis (2.7%), self-mutilation (2.7%), combined immune deficiency (2.7%) and kernicterus (2.7%). There was no correlation of residual enzyme activity to severity, clinical presentation, liver function tests, liver biopsy findings or outcome apart from highly significant correlation with repeated chest infections (P = 0.001). Duration to diagnosis and exposure to galactose in diet correlated with liver pathology severity i.e. hepatocyte necrosis (P = 0.003) and cytoskeleton damage (P = 0.003), but not to outcome. Galactosemia should be suspected in any child with liver, neurologic disease and/ or immunodeficiency. Its complications are potentially preventable.
11/29/2019 2:03:03 PM +00:00
A review on pregnancy complicated by ovarian epithelial and nonepithelial malignant tumors: Diagnostic and therapeutic perspectives
The management of gestational ovarian cancer can be challenging because of the risk of fetal wastage, and the possibility of treatment-related complications to the fetus; it is based on insufficient data from retrospective studies and case series. Here, a literature review of the diagnostic and surgical approaches to the gestational ovarian cancer has been performed; moreover, data on safety of chemotherapeutic treatments in pregnancy, including both oncologic and fetal outcomes, have also been reviewed. Up to now, 193 cases of ovarian cancers during pregnancy have been reported in the English literature. Treatment of ovarian malignancies during pregnancy depends on histology, stage, and gestational weeks. When possible, surgical excision is indicated, and fertility-sparing surgery can be offered to stage I epithelial ovarian tumours (EOC), germ cell ovarian, or sex-cord stromal ovarian tumours. Neoadjuvant and/or adjuvant chemotherapy for advanced ovarian tumours is indicated as in non-pregnant women. Administration of chemotherapy after the first trimester, can cause fetal growth restriction, while being seemingly safe. The therapeutic approach of ovarian cancer in pregnancy should be individualized and intended in specialized centers.
11/29/2019 1:53:55 PM +00:00
pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy
Nanoparticle-mediated targeted delivery of bioactive natural compounds has recently been gaining much interest for breast cancer therapy. Herein, phenyl boronic acid (PBA)-conjugated and pH-responsive ZnO nanoparticles (diameter 40 nm) were synthesized for the tumor tissue-specific delivery of curcumin. PBA conjugation facilitates the targeted delivery of curcumin to the sialic acid overexpressed in breast cancer cell membranes. Curcumin-loaded ZnO nanoparticles (ZnO-PBA-Curcumin) caused apoptotic cell death in MCF-7 human breast cancer cells by inducing oxidative stress and mitochondrial damage. Further, in vivo intravenous (i.v.) administration of ZnO-PBA-Curcumin was found to effectively decrease tumor growth in Ehrlich ascites carcinoma (EAC) tumor-bearing mice via the enhanced accumulation of curcumin. Interestingly, ZnO-PBA-Curcumin did not show any signs of systemic toxicity. The cytotoxic potential of the nanohybrid ZnO-PBA-Curcumin is attributed to the combinatorial cytotoxic effects of curcumin and ZnO in cancer cells. Collectively, ZnO-PBA-Curcumin may represent a potential treatment modality for breast cancer therapy. This study provides insight into the tumor cell targeting mechanism using PBA functionalization, and the anticancer efficacy of curcumin-loaded pH-sensitive nanohybrids can be attributed to the differential oxidative stress-inducing properties of curcumin and Zn+2 ions.
11/29/2019 1:37:59 PM +00:00
Multiplex polymerase chain reaction (M-PCR) for bacterial vaginosis detection
Bacterial vaginosis (BV) is one of the most common vaginal infections in women of reproductive age. If not treated promptly, the disease can lead to serious complications affecting the fertility and long-term health of women. Research on BV requires effort from a variety of disciplines and its treatment can only be determined by coordinated actions in research and treatment. Currently, BV diagnostic methods are often based on culture techniques and Gram staining. However, molecular biology research is developing and has proved to more advantageous for identifying key pathogens. Combining both methods, we conducted a study to develop a diagnostic procedure using multiplex polymerase chain reaction (M-PCR) for simultaneous and accurate detection of the bacterial species that cause BV, incurring minimal costs and time for testing.
11/29/2019 12:27:37 PM +00:00
Ứng dụng kỹ thuật Microsattelite DNA trong chẩn đoán trước sinh bệnh loạn dưỡng cơ Duchenne
Loạn dưỡng cơ Duchenne là bệnh lý di truyền thần kinh cơ hay gặp nhất trong nhóm bệnh lý loạn dưỡng cơ do đột biến gen dystrophin trên nhiễm sắc thể X. Chẩn đoán trước sinh các bà mẹ mang thai có nguy cơ sinh con bị bệnh giúp phát hiện các trường hợp thai mắc loạn dưỡng cơ Duchenne. Ứng dung kỹ thuật Microsatellite DNA trong chẩn đoán trước sinh bệnh loạn dưỡng cơ Duchenne. 05 thai phụ mang thai từ 17 - 22 tuần được xác định là người mang gen. Tách chiết DNA từ tế bào ối, máu ngoại vi của bệnh nhân và thai phụ, hoàn thiện và ứng dụng kỹ thuật Microsatellite - DNA để chẩn đoán trước sinh và so sánh kết quả với kỹ thuật phát hiện đột biến gen trực tiếp. Kỹ thuật xác định đột biến trực tiếp và kỹ thuật Microsatellite - DNA có kết quả trùng khớp nhau cho thấy đã hoàn thiện được kỹ thuật Microsatellite - DNA. 1/5 thai nhi được chẩn đoán mắc bệnh, thai phụ được tư vấn và đình chỉ thai nghén. 4/5 thai nhi được chẩn đoán bình thường, tiếp tục theo dõi thai.
11/29/2019 4:31:28 AM +00:00
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Đặc điểm trầm cảm ở bệnh nhân nữ có rối loạn hỗn hợp lo âu và trầm cảm ở độ tuổi 45 - 59
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